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您現(xiàn)在的位置: 醫(yī)學全在線 > 考研院校 > 華中華南 > 廣州醫(yī)科大學 > 導師信息 > 正文:廣州醫(yī)學院導師蔣義國簡介
    

廣州醫(yī)學院導師蔣義國信息介紹

更新時間:2012/6/11 醫(yī)學考研論壇 在線題庫 評論

二、2008年以來SCI論文
1. Qiaoyuan Yang, Zhigang Jie, Sheng Ye, Zhengrong Li, Zhiyuan Han, Jianjun Wu,Yuanqi Li, Chengfeng Yang, Yiguo Jiang(通訊作者). Genetic variations in miR-27a gene decrease mature miR-27a level and reduce gastric cancer susceptibility. Oncogene. 2012 (revised). (SCI IF: 7.414)
2. Yiguo Jiang (通訊作者),Yan Wu, Anne R. Greenlee, Jianjun Wu, Zhiyuan Han, Xun Li,Yao Zhao. miR-106a-mediated malignant transformation of cells induced by anti- benzo[a]pyrene-trans-7,8-diol-9,10-epoxide. Toxicological Sciences. 2011;119(1): 50-60. (SCI IF: 5.093)
3. Qiaoyuan Yang, Zhigang Jie, Hong Cao, Anne R. Greenlee, Chengfeng Yang, Fei Zou,Yiguo Jiang(通訊作者). Low-level expression of let-7a in gastric cancer and its involvement in tumorigenesis by targeting RAB40C. zxtf.net.cn Carcinogenesis. 2011;32(5):713-722. (SCI IF: 5.402)
4. Zhiyuan Han, Qiaoyuan Yang, Bingbing Liu, Jianjun Wu, Yuanqi Li,Chengfeng Yang, Yiguo Jiang(通訊作者). MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol. Carcinogenesis, 2012;33(1):131-139. (SCI IF: 5.402)
5. Zhishan Wang, Junling Yang, Theresa Fisher, Hua Xiao, Yiguo Jiang, Chengfeng Yang. Akt activation is responsible for enhanced migratory and invasive behavior of arsenic-transformed human bronchial epithelial cells. Environmental Health Perspectives. 2012;120(1):92-97.(SCI IF: 6.087)
6. Yong Zhao, Zhishan Wang, Yiguo Jiang, Chengfeng Yang. Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells. Cancer Letters. 2011;313:54-63.(SCI IF: 4.864)
7. Yao Zhao, Huanying Liu, Yuanqi Li, Jianjun Wu, Anne R. Greenlee, Chengfeng Yang, Yiguo Jiang(通訊作者). The role of miR-506 in transformed 16HBE cells induced by anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide. Toxicology Letters. 2011;205(3):320-326. (SCI IF: 3.581)
8. Linhua Liu, Yiguo Jiang (通訊作者), Hongyu Zhang, Anne R. Greenlee, Rian Yu, Qiaoyuan Yang. MiR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide. Toxicology in Vitro. 2010;24(4):1168-1175. (SCI IF: 2.546)
9. Huihan Duan, Yiguo Jiang (通訊作者), Hongyu Zhang, Yan Wu. MiR-320 and miR-494 affect cell cycles of primary zxtf.net.cn murine bronchial epithelial cells exposed to benzo(a)pyrene. Toxicology in Vitro. 2010;24(3):928-935. (SCI IF: 2.546)
10. Linhua Liu, Yiguo Jiang (通訊作者), Hongyu Zhang,Anne R.Greenlee, Zhiyuan Han. Overexpressed miR-494 down-regulates PTEN gene expression in cells transformed by anti-benzo(a)pyrene-trans-7,8- dihydrodiol-9,10-epoxide. Life Sciences. 2010;86(5-6):192-198. (SCI IF: 2.451)
11. Yiguo Jiang(通訊作者), Juan Fu, Anne R. Greenlee, Yuelan Shen, Huihan Duan and Xuemin Chen. Effects of silencing of HER2/neu gene in anti-BPDE-transformed cells. Toxicology in Vitro.2009;23(1):53-59. (SCI IF: 2.546)12. Yuelan Shen, Yiguo Jiang(通訊作者), Anne R.Greenlee, Lanlan Zhou and Linhua Liu. MicroRNA expression profiles and miR-10a target in anti-benzo[a]pyrene-7,8-diol-9,10- epoxide-transformed human 16HBE cells. Biomedical and Environmental Sciences.2009; 22(1):14-21. (SCI IF: 1.063)
13. Lanlan Zhou, Yiguo Jiang(通訊作者),Aijun Tan, Anne R Greenlee, Yuelan Shen, Linhua Liu and Qiaoyuan Yang. Silencing of N-Ras gene expression using shRNA decreases transformation efficiency and tumor growth in transformed cells induced by anti-BPDE. Toxicological Sciences.2008;105(2):286-294. (SCI IF: 5.093)

三、2008年以來科研成果與獲獎論文(僅列第一完成人)
1. 2008年廣東省科學技術(shù)成果獎二等獎,肺癌化學病因及其干預的實驗研究,第一完成人。(本項目還獲得廣州市科學技術(shù)成果獎一等獎和中華預防醫(yī)學會科學技術(shù)成果獎三等獎)
2. 2011年廣東省優(yōu)秀碩士學位論文,miR-106a和miR-17-5p在反式二羥環(huán)氧苯并芘誘導細胞惡變中的作用,研究生論文導師。
3. 2010年廣東省優(yōu)秀碩士學位論文zxtf.net.cn,反式二羥環(huán)氧苯并芘誘導惡變細胞中miR-494和miR-22對PTEN基因調(diào)控及其功能研究,研究生論文導師。
4. 2009年(首屆)廣東省優(yōu)秀碩士學位論文,RNA干擾技術(shù)研究N-Ras基因表達改變在人支氣管上皮細胞惡變中的作用,研究生論文導師。

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