聶紅,女,博士,副研究員,上海交通大學醫(yī)學院免疫學教研室,碩士生導師。1993年畢業(yè)于上海第二醫(yī)科大學臨床醫(yī)學專業(yè),獲學士學位;1996年畢業(yè)于上海第二醫(yī)科大學免疫學專業(yè),獲碩士學位;2004年畢業(yè)于上海第二醫(yī)科大學免疫學專業(yè),獲博士學位。曾于1997年10月至1998年9月赴德國Konstanz大學生物系進修;2005年2月至2005年8月在美國Baylor醫(yī)學院從事博士后研究。目前承擔上海市教委基金項目一項,參與國家自然科學基金重大項目和上海市科委重大科技攻關項目等多項。參與的科研項目《類風濕關節(jié)炎的新藥物靶點及特異性疫苗治療》獲2005年上海市科技進步三等獎。
研究方向:自身免疫病與免疫調(diào)節(jié)
近兩年發(fā)表的論文:
1.Wan B, Nie H, Liu AL, Feng GZ, He DY, Xu R, Zhang Q, Dong C, Zhang JZ. Aberrant regulation of synovial T cell activation by soluble co-stimulatory molecules in rheumatoid arthritis. J Immunol. 2006, in press IF:6.4
2.Nie H, Wu JL, Zhang M, Xu J, Zou MH. Endothelial nitric oxide synthase-dependent tyrosine nitration of prostacyclin synthase in diabetes in vivo. Diabetes. 2006;55(11):3133-41 IF:7.7
3.Jian Hong, Ying Zang, Hong Nie, and Jingwu Z Zhang. CD4+ Regulatory T Cell Responses Induced by T Cell Vaccination in Patients with Multiple Sclerosis. PNAS 2006;103(13):5024-9 IF:10.5
4.W Sun, H Nie (co-first author), N Li, YCQ Zang, D Zhang, G Feng, L Ni, R Xu, S Prasad, RR Robinson, W Ho, E Sercarz, and JZ Zhang. Skewed T cell receptor BV14 and BV16 expression and shared CDR3 sequence and common sequence motifs in synovial T cells of rheumatoid arthritis. Genes & Immunity 2005;6:248-61 IF:3.8
5.Guangwu Xu, Hong Nie (co-first author), Ningli Li, Wenxin Zhang, Dongqing Zhang, Guozhang Feng, Liqing Ni, Rong Xu, Jian Hong, and Jingwu Z. Zhang. Functional role and molecular mechanism of osteopontin in amplication and perpetuation of rheumatoid synovitis. Journal of Clinical Investigation 2005;115(4):1060-7 IF:14.3
6.Guangwu Xu, Wei Sun, Dongyi He, Li Wang, Wenxin Zheng, Hong Nie, Liqing Ni, Dongqing Zhang, Ningli Li, and Jingwu Zhang. Overexpression of osteopontin in rheumatoid synovial mononuclear cells is associated with joint inflammation, not with genetic polymorphism. The Journal of Rheumatology 2005;32:410-6 IF:3.0
聯(lián)系方式:
地址:上海市重慶南路280號五號樓1209室
郵政編碼:200025
電子郵箱:hnie@sibs.ac.cn